The trailer came out at the recent panel at Comic Con and had Will Ferrell, Jonah Hill and Tina Fey with a cut out of Brad Pitt. It is like a hilarious homage to Marlon Brando.

The trailer is via Yahoo.

Synopsis via Comicbookmovie

Megamind (Will Ferrell) and his life-long archenemy, Metro Man (Brad Pitt) are aliens that were sent away from their respective home planets in time of crisis. Megamind, taking the role of super villain, continuously loses in battle to Metro Man. It seems that the pattern will never cease until Megamind apparently kills him with a solar-powered satellite during one of his many hostage plots. Now freed from his rival’s shadow, Megamind proceeds to take control of Metro City, and at first, enjoys his sinister freedom. But after a while, he becomes unhappy with having no real purpose in life anymore without an enemy, and decides to appease his depression by turning a lonely cameraman named Hal (Jonah Hill) into Metro City’s next big superhero, the fiery headed Titan. Unfortunately, Titan decides to utilize his new power against humanity as revenge for the lifetime of rejection he has endured, forcing Megamind to do the inevitable: become the hero of the crisis. Aided by his childhood sidekick Minion (David Cross), Megamind now sets out to stop Titan’s rampage of destruction.

The trailer shows the death of Metro Man finally and for the first time and also features Will’s homage to Marlon Brando portrayed by the main character Jor El in the Superman movies.